Naturally occurring canine models of several types of neuronal ceroid lipofuscinoses (NCLs), also known as Batten disease, may aid…
Articles by Marta Figueiredo, PhD
Researchers have identified eight potential biomarkers of disease severity, progression and treatment response in children with late infantile Batten…
CLN3, the protein lacking in the juvenile form of Batten disease (CLN3 disease), is involved in maintaining water balance, which is…
Caspase-1 — an enzyme involved in several cellular processes, including inflammatory responses — is a potential therapeutic target to revert…
Researchers have found a natural model of CLN7 disease, a rare form of Batten disease, in a type…
Researchers have found common disease mechanisms between a type of Batten disease and a form of adult neurodegenerative disease. The study,…
Researchers have developed a new newborn screening test that uses dried blood spots to more accurately diagnose late infantile Batten…
Researchers have identified five new mutations in the CLN8 gene — the genetic factor behind CLN8 disease, one of…
A genetically modified mouse with increased levels of a specific enzyme in the brain, along with a new genetic tool,…