The levels of abnormal storage material inside certain immune cells could be used as a biomarker of disease activity and…
Articles by Marisa Wexler, MS
Theranexus and Inserm Transfert have entered an agreement to work toward the development of treatment candidates for neurological disorders…
Levels of fatty molecules called glycerophosphodiesters, or GPDs, are elevated in the blood and other bodily fluids of people with…
The CLN3 protein, defects of which cause juvenile Batten disease, is needed for the breakdown and clearance of the…
An experimental enzyme replacement therapy (ERT) — one injected directly into the brain — was found to lessen motor…
Mutations in the gene KCTD7, known to cause a rare form of Batten disease, lead to the excessive accumulation in…
Drinking acidified water prevented motor impairment and decreased the toxic accumulation of molecular debris in brain cells in a mouse…
Children with late infantile Batten disease on approved enzyme replacement therapy show signs of age-related degeneration in the light-sensing part…
Six months of treatment with cannabidiol (CBD) reduced brain inflammation in a mouse model of infantile Batten disease, but…
People with juvenile Batten disease may be at increased risk of developing an abnormally high body temperature when taking…