Researchers Discover New Gene Variant Associated with Adult-onset Batten Initially Missed by Genetic Tests

A previously unidentified variant of a gene associated with adult-onset Batten disease (ANCL) was found in an affected family after initial genetic tests failed, highlighting the difficulties in diagnosing this condition despite advances in DNA sequencing technology, a new study shows.  The…

Gene Therapy Decreased Protein Aggregates in Animal Model of Batten Disease, Study Finds

Gene therapy is able to reduce toxic protein aggregates in a zebrafish model of one form of adult-onset Batten disease, a new study from China shows. The study, “Gene Therapy of Adult Neuronal Ceroid Lipofuscinoses with CRISPR/Cas9 in Zebrafish,” appeared in the journal Human Gene Therapy. The study’s…